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CATH Classification

Domain Context

CATH Clusters

Superfamily 4.10.40.60
Functional Family

Enzyme Information

UniProtKB Entries (1)

P61095
SFI1_SEGFL
Segestria florentina
Mu-segestritoxin-Sf1a

PDB Structure

PDB 2MF3
External Links
Method SOLUTION NMR
Organism
Primary Citation
The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large beta-hairpin loop.
Bende, N.S., Dziemborowicz, S., Herzig, V., Ramanujam, V., Brown, G.W., Bosmans, F., Nicholson, G.M., King, G.F., Mobli, M.
Febs J.
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