CATH Domain 2mc3A00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	Crossover junction endonuclease MUS81

Enzyme Information

3.1.22.-

Endodeoxyribonucleases producing other than 5'-phosphomonoesters.

based on mapping to UniProt Q96NY9

UniProtKB Entries (1)

MUS81_HUMAN

Homo sapiens

Crossover junction endonuclease MUS81

PDB Structure

PDB	2MC3
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	A winged helix domain in human MUS81 binds DNA and modulates the endonuclease activity of MUS81 complexes. Fadden, A.J., Schalbetter, S., Bowles, M., Harris, R., Lally, J., Carr, A.M., McDonald, N.Q. Nucleic Acids Res.