×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily S15/NS1, RNA-binding
Functional Family histidine--tRNA ligase, cytoplasmic isoform X6

Enzyme Information

6.1.1.21
Histidine--tRNA ligase.
based on mapping to UniProt P12081
ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).

UniProtKB Entries (1)

P12081
SYHC_HUMAN
Homo sapiens
Histidine--tRNA ligase, cytoplasmic

PDB Structure

PDB 2LW7
External Links
Method SOLUTION NMR
Organism
Primary Citation
NMR solution structure of human HisRS splice variant
Ye, F., Wei, Z., Wu, J., Schimmel, P., Zhang, M.
To be Published
CATH-Gene3D is a Global Biodata Core Resource Learn more...