CATH Domain 2lkoA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Fermitin family homolog 2 (Drosophila)

Enzyme Information

UniProtKB Entries (1)

FERM2_HUMAN

Homo sapiens

Fermitin family homolog 2

PDB Structure

PDB	2LKO
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation. Liu, J., Fukuda, K., Xu, Z., Ma, Y.Q., Hirbawi, J., Mao, X., Wu, C., Plow, E.F., Qin, J. J.Biol.Chem.