CATH Domain 2l9nA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.900	SBDS protein C-terminal domain, subdomain 1

Domain Context

CATH Clusters

Superfamily	SBDS protein C-terminal domain, subdomain 1
Functional Family	SBDS, ribosome maturation factor

Enzyme Information

UniProtKB Entries (1)

SBDS_HUMAN

Homo sapiens

Ribosome maturation protein SBDS

PDB Structure

PDB	2L9N
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Finch, A.J., Hilcenko, C., Basse, N., Drynan, L.F., Goyenechea, B., Menne, T.F., Gonzalez Fernandez, A., Simpson, P., D'Santos, C.S., Arends, M.J., Donadieu, J., Bellanne-Chantelot, C., Costanzo, M., Boone, C., McKenzie, A.N., Freund, S.M., Warren, A.J. Genes Dev.