CATH Domain 2l2aA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.70	Distorted Sandwich
	2.70.130	Cation-dependent Mannose-6-phosphate Receptor; Chain A
	2.70.130.10	Mannose-6-phosphate receptor binding domain

Domain Context

CATH Clusters

Superfamily	Mannose-6-phosphate receptor binding domain
Functional Family	Insulin-like growth factor 2 receptor

Enzyme Information

UniProtKB Entries (1)

MPRI_HUMAN

Homo sapiens

Cation-independent mannose-6-phosphate receptor

PDB Structure

PDB	2L2A
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution. Williams, C., Hoppe, H.J., Rezgui, D., Strickland, M., Forbes, B.E., Grutzner, F., Frago, S., Ellis, R.Z., Wattana-Amorn, P., Prince, S.N., Zaccheo, O.J., Nolan, C.M., Mungall, A.J., Jones, E.Y., Crump, M.P., Hassan, A.B. Science