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CATH Classification

Domain Context

CATH Clusters

Superfamily Dbl homology (DH) domain
Functional Family Guanine nucleotide exchange factor DBS

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P97924
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P97924
KALRN_RAT
Rattus norvegicus
Kalirin

PDB Structure

PDB 2KR9
External Links
Method SOLUTION NMR
Organism
Primary Citation
The solution NMR structure of the first Dbl domain of RhoGEF Kalirin.
Gorbatyuk, V.Y., Schiller, M.R., Hoch, J.C.
To be Published
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