CATH Domain 2kncB00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.5	Single alpha-helices involved in coiled-coils or other helix-helix interfaces
	1.20.5.100	Cytochrome c1, transmembrane anchor, C-terminal

Domain Context

CATH Clusters

Superfamily	Cytochrome c1, transmembrane anchor, C-terminal
Functional Family	Integrin beta

Enzyme Information

UniProtKB Entries (1)

ITB3_HUMAN

Homo sapiens

Integrin beta-3

PDB Structure

PDB	2KNC
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation. Yang, J., Ma, Y.Q., Page, R.C., Misra, S., Plow, E.F., Qin, J. Proc.Natl.Acad.Sci.USA