CATH Domain 2k85A00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.440	FF domain

Domain Context

CATH Clusters

Superfamily	FF domain
Functional Family	Rho GTPase activating protein 35

Enzyme Information

UniProtKB Entries (1)

RHG35_HUMAN

Homo sapiens

Rho GTPase-activating protein 35

PDB Structure

PDB	2K85
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	NMR structural studies on human p190-A RhoGAPFF1 revealed that domain phosphorylation by the PDGF-receptor alpha requires its previous unfolding. Bonet, R., Ruiz, L., Aragon, E., Martin-Malpartida, P., Macias, M.J. J.Mol.Biol.