CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.10 | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
Domain Context
CATH Clusters
| Superfamily | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
| Functional Family | Phenazine-specific methyltransferase |
Enzyme Information
| 2.1.1.327 |
Phenazine-1-carboxylate N-methyltransferase.
based on mapping to UniProt Q9HWH2
S-adenosyl-L-methionine + phenazine-1-carboxylate = S-adenosyl-L- homocysteine + 5-methylphenazine-1-carboxylate.
-!- The enzyme, characterized from the bacterium Pseudomonas aeruginosa, is involved in the biosynthesis of pyocyanin, a toxin produced and secreted by the organism. -!- The enzyme is active in vitro only in the presence of EC 1.14.13.218.
|
UniProtKB Entries (1)
| Q9HWH2 |
PHZM_PSEAE
Pseudomonas aeruginosa PAO1
Phenazine-1-carboxylate N-methyltransferase
|
PDB Structure
| PDB | 2IP2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa.
Biochemistry
|
