×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 2i5jB04

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.70 Alpha-Beta Plaits
Homologous Superfamily 3.30.70.270 Reverse transcriptase/Diguanylate cyclase domain

Domain Context

CATH Clusters

Superfamily 3.30.70.270
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (2)

P03366
POL_HV1B1
Human immunodeficiency virus type 1 BH10
Gag-Pol polyprotein
Q8UM83
Q8UM83_9HIV1
Human immunodeficiency virus 1
Pol protein

PDB Structure

PDB 2I5J
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
HIV-1 reverse transcriptase structure with RNase H inhibitor dihydroxy benzoyl naphthyl hydrazone bound at a novel site.
Himmel, D.M., Sarafianos, S.G., Dharmasena, S., Hossain, M.M., McCoy-Simandle, K., Ilina, T., Clark, A.D., Knight, J.L., Julias, J.G., Clark, P.K., Krogh-Jespersen, K., Levy, R.M., Hughes, S.H., Parniak, M.A., Arnold, E.
Acs Chem.Biol.
CATH-Gene3D is a Global Biodata Core Resource Learn more...