CATH Domain 2hwyA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1010	5'-nuclease

Domain Context

CATH Clusters

Superfamily	5'-nuclease
Functional Family	protein SMG5 isoform X2

Enzyme Information

UniProtKB Entries (1)

SMG5_HUMAN

Homo sapiens

Protein SMG5

PDB Structure

PDB	2HWY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. Glavan, F., Behm-Ansmant, I., Izaurralde, E., Conti, E. Embo J.