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1 keywords

CATH Domain 2gutA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.246 Serum Albumin; Chain A, Domain 1
Homologous Superfamily 1.10.246.20 Coactivator CBP, KIX domain

Domain Context

CATH Clusters

Superfamily Coactivator CBP, KIX domain
Functional Family Mediator of RNA polymerase II transcription subunit 15

Enzyme Information

UniProtKB Entries (1)

Q96RN5
MED15_HUMAN
Homo sapiens
Mediator of RNA polymerase II transcription subunit 15

PDB Structure

PDB 2GUT
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.
Yang, F., Vought, B.W., Satterlee, J.S., Walker, A.K., Jim Sun, Z.-Y., Watts, J.L., Debeaumont, R., Mako Saito, R., Hyberts, S.G., Yang, S., Macol, C., Iyer, L., Tjian, R., van den Heuvel, S., Hart, A.C., Wagner, G., Naar, A.M.
Nature
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