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CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.630.30
Functional Family dTDP-fucosamine acetyltransferase

Enzyme Information

2.3.1.210
dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase.
based on mapping to UniProt Q8FBQ3
Acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose = CoA + dTDP-4- acetamido-4,6-dideoxy-alpha-D-galactose.
-!- The product, TDP-4-acetamido-4,6-dideoxy-D-galactose, is utilized in the biosynthesis of Enterobacterial Common Antigen (ECA).

UniProtKB Entries (1)

Q8FBQ3
WECD_ECOL6
Escherichia coli CFT073
DTDP-fucosamine acetyltransferase

PDB Structure

PDB 2FS5
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of TDP-Fucosamine Acetyltransferase (WecD) from Escherichia coli, an Enzyme Required for Enterobacterial Common Antigen Synthesis.
Hung, M.N., Rangarajan, E., Munger, C., Nadeau, G., Sulea, T., Matte, A.
J.Bacteriol.
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