CATH Domain 2fprB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1000	HAD superfamily/HAD-like

Domain Context

CATH Clusters

Superfamily	HAD superfamily/HAD-like
Functional Family	Histidine biosynthesis bifunctional protein HisB

Enzyme Information

4.2.1.19	Imidazoleglycerol-phosphate dehydratase. based on mapping to UniProt Q9S5G5 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2- oxopropyl phosphate + H(2)O.
3.1.3.15	Histidinol-phosphatase. based on mapping to UniProt Q9S5G5 L-histidinol phosphate + H(2)O = L-histidinol + phosphate.

UniProtKB Entries (1)

HIS7_ECO57

Escherichia coli O157:H7

Histidine biosynthesis bifunctional protein HisB

PDB Structure

PDB	2FPR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway. Rangarajan, E.S., Proteau, A., Wagner, J., Hung, M.N., Matte, A., Cygler, M. J.Biol.Chem.