×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily YojJ-like
Functional Family Diadenylate cyclase

Enzyme Information

2.7.7.85
Diadenylate cyclase.
based on mapping to UniProt Q812L9
2 ATP = 2 diphosphate + cyclic di-3',5'-adenylate.
-!- Cyclic di-3',5'-adenylate is a bioactive molecule produced by some bacteria and archaea, which may function as a secondary signaling molecule. -!- The intracellular bacterial pathogen Listeria monocytogenes secretes it into the host's cytosol, where it triggers a cytosolic pathway of innate immunity.

UniProtKB Entries (1)

Q812L9
Q812L9_BACCR
Bacillus cereus ATCC 14579
Diadenylate cyclase

PDB Structure

PDB 2FB5
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of the hypothetical membrane spanning protein from Bacillus cereus
Zhang, R., Zhou, M., Ginell, S., Abdullah, J., Collart, F., Joachimiak, A.
To be Published
CATH-Gene3D is a Global Biodata Core Resource Learn more...