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CATH Classification

Domain Context

CATH Clusters

Superfamily 6.10.140.410
Functional Family

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q15788
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (2)

Q15788
NCOA1_HUMAN
Homo sapiens
Nuclear receptor coactivator 1
P45481
CBP_MOUSE
Mus musculus
CREB-binding protein

PDB Structure

PDB 2C52
External Links
Method SOLUTION NMR
Organism
Primary Citation
Structural diversity in p160/CREB-binding protein coactivator complexes.
Waters, L., Yue, B., Veverka, V., Renshaw, P., Bramham, J., Matsuda, S., Frenkiel, T., Kelly, G., Muskett, F., Carr, M., Heery, D.M.
J. Biol. Chem.
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