CATH Domain 2bduB01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1000	HAD superfamily/HAD-like

Domain Context

CATH Clusters

Superfamily	HAD superfamily/HAD-like
Functional Family

Enzyme Information

3.1.3.5	5'-nucleotidase. based on mapping to UniProt Q9D020 A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate. -!- Wide specificity for 5'-nucleotides.
3.1.3.91	7-methylguanosine nucleotidase. based on mapping to UniProt Q9D020 (1) N(7)-methyl-GMP + H(2)O = N(7)-methyl-guanosine + phosphate. (2) CMP + H(2)O = cytidine + phosphate. -!- The enzyme also has low activity with N(7)-methyl-GDP, producing N(7)-methyl-GMP. -!- Does not accept AMP or GMP, and has low activity with UMP.

UniProtKB Entries (1)

5NT3A_MOUSE

Mus musculus

Cytosolic 5'-nucleotidase 3A

PDB Structure

PDB	2BDU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning. Bitto, E., Bingman, C.A., Wesenberg, G.E., McCoy, J.G., Phillips, G.N. J.Biol.Chem.