CATH Domain 2b92B00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Guanylate-binding protein 1

Enzyme Information

3.6.5.-

Acting on GTP; involved in cellular and subcellular movement.

based on mapping to UniProt P32455

UniProtKB Entries (1)

GBP1_HUMAN

Homo sapiens

Guanylate-binding protein 1

PDB Structure

PDB	2B92
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP. Ghosh, A., Praefcke, G.J., Renault, L., Wittinghofer, A., Herrmann, C. Nature