CATH Domain 2b77B00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.180	Transthyretin/hydroxyisourate hydrolase domain

Domain Context

CATH Clusters

Superfamily	Transthyretin/hydroxyisourate hydrolase domain
Functional Family	Transthyretin

Enzyme Information

UniProtKB Entries (1)

TTHY_HUMAN

Homo sapiens

Transthyretin

PDB Structure

PDB	2B77
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis. Adamski-Werner, S.L., Palaninathan, S.K., Sacchettini, J.C., Kelly, J.W. J.Med.Chem.