CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.226 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
|
3.90.226.10 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
| Functional Family | Propionyl-CoA carboxylase, beta subunit |
Enzyme Information
| 6.4.1.3 |
Propionyl-CoA carboxylase.
based on mapping to UniProt P9WQH7
ATP + propanoyl-CoA + HCO(3)(-) = ADP + phosphate + (S)-methylmalonyl- CoA.
-!- Also carboxylates butanoyl-CoA and catalyzes transcarboxylation.
|
UniProtKB Entries (1)
| P9WQH7 |
PCC5_MYCTU
Mycobacterium tuberculosis H37Rv
Probable propionyl-CoA carboxylase beta chain 5
|
PDB Structure
| PDB | 2A7S |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.Usa
|
