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1 keywords

CATH Domain 2a7rC00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family GMP reductase

Enzyme Information

1.7.1.7
GMP reductase.
based on mapping to UniProt Q9P2T1
Inosine 5'-phosphate + NH(3) + NADP(+) = guanosine 5'-phosphate + NADPH.
-!- Formerly EC 1.6.6.8.

UniProtKB Entries (1)

Q9P2T1
GMPR2_HUMAN
Homo sapiens
GMP reductase 2

PDB Structure

PDB 2A7R
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of Human Guanosine Monophosphate Reductase 2 (GMPR2) in Complex with GMP
Li, J., Wei, Z., Zheng, M., Gu, X., Deng, Y., Qiu, R., Chen, F., Ji, C., Gong, W., Xie, Y., Mao, Y.
J.Mol.Biol.
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