CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1050 | Beta-carbonic Anhydrase; Chain A |
|
3.40.1050.10 | Carbonic anhydrase |
Domain Context
CATH Clusters
| Superfamily | Carbonic anhydrase |
| Functional Family | Carbonic anhydrase |
Enzyme Information
| 4.2.1.1 |
Carbonic anhydrase.
based on mapping to UniProt P9WPJ9
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.
|
UniProtKB Entries (1)
| P9WPJ9 |
MTCA2_MYCTU
Mycobacterium tuberculosis H37Rv
Carbonic anhydrase 2
|
PDB Structure
| PDB | 2A5V |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural Mechanics of the pH-dependent Activity of beta-Carbonic Anhydrase from Mycobacterium tuberculosis
J.Biol.Chem.
|
