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1 keywords

CATH Domain 2a2cA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.70 Alpha-Beta Plaits
Homologous Superfamily 3.30.70.3170  

Domain Context

CATH Clusters

Superfamily 3.30.70.3170
Functional Family galactokinase isoform X1

Enzyme Information

2.7.1.157
N-acetylgalactosamine kinase.
based on mapping to UniProt Q01415
ATP + N-acetyl-alpha-D-galactosamine = ADP + N-acetyl-alpha-D- galactosamine 1-phosphate.
-!- The enzyme is highly specific for GalNAc as substrate, but has slight activity with D-galactose.

UniProtKB Entries (1)

Q01415
GALK2_HUMAN
Homo sapiens
N-acetylgalactosamine kinase

PDB Structure

PDB 2A2C
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The molecular architecture of human N-acetylgalactosamine kinase.
Thoden, J.B., Holden, H.M.
J.Biol.Chem.
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