CATH Domain 1ydkA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.30	Glutaredoxin
	3.40.30.10	Glutaredoxin

Domain Context

CATH Clusters

Superfamily	Glutaredoxin
Functional Family

Enzyme Information

2.5.1.18	Glutathione transferase. based on mapping to UniProt P08263 RX + glutathione = HX + R-S-glutathione. -!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.
1.11.1.-	Peroxidases. based on mapping to UniProt P08263
5.3.3.-	Transposing C=C bonds. based on mapping to UniProt P08263

UniProtKB Entries (1)

GSTA1_HUMAN

Homo sapiens

Glutathione S-transferase A1

PDB Structure

PDB	1YDK
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Tertiary Interactions Stabilise the C-terminal Region of Human Glutathione Transferase A1-1: a Crystallographic and Calorimetric Study. Kuhnert, D.C., Sayed, Y., Mosebi, S., Sayed, M., Sewell, T., Dirr, H.W. J.Mol.Biol.