×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.-
Serine endopeptidases.
based on mapping to UniProt Q04756

UniProtKB Entries (1)

O43278
SPIT1_HUMAN
Homo sapiens
Kunitz-type protease inhibitor 1

PDB Structure

PDB 1YC0
External Links
Method X-RAY DIFFRACTION
Organism Spodoptera
Primary Citation
Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B.
Shia, S., Stamos, J., Kirchhofer, D., Fan, B., Wu, J., Corpuz, R.T., Santell, L., Lazarus, R.A., Eigenbrot, C.
J.Mol.Biol.
CATH-Gene3D is a Global Biodata Core Resource Learn more...