CATH Domain 1wq1G02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.506	GTPase Activation - p120GAP; domain 1
	1.10.506.10	GTPase Activation - p120gap; domain 1

Domain Context

CATH Clusters

Superfamily	GTPase Activation - p120gap; domain 1
Functional Family	RAS p21 protein activator 1

Enzyme Information

UniProtKB Entries (1)

RASH_HUMAN

Homo sapiens

GTPase HRas

PDB Structure

PDB	1WQ1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Scheffzek, K., Ahmadian, M.R., Kabsch, W., Wiesmuller, L., Lautwein, A., Schmitz, F., Wittinghofer, A. Science