CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1240 | Phosphoglycerate mutase-like |
Domain Context
CATH Clusters
Superfamily | Phosphoglycerate mutase-like |
Functional Family | 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform 2 |
Enzyme Information
2.7.1.105 |
6-phosphofructo-2-kinase.
based on mapping to UniProt P07953
ATP + D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate.
-!- Not identical with EC 2.7.1.11. -!- The enzyme copurifies with EC 3.1.3.46.
|
3.1.3.46 |
Fructose-2,6-bisphosphate 2-phosphatase.
based on mapping to UniProt P07953
Beta-D-fructose 2,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The enzyme copurifies with EC 2.7.1.105 (cf. EC 3.1.3.54).
|
UniProtKB Entries (1)
P07953 |
F261_RAT
Rattus norvegicus
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
|
PDB Structure
PDB | 1TIP |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal structure of a trapped phosphoenzyme during a catalytic reaction.
Nat.Struct.Biol.
|