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1 keywords

CATH Domain 1senA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.30 Glutaredoxin
Homologous Superfamily 3.40.30.10 Glutaredoxin

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family thioredoxin domain-containing protein 12

Enzyme Information

1.8.4.2
Protein-disulfide reductase (glutathione).
based on mapping to UniProt O95881
2 glutathione + protein-disulfide = glutathione disulfide + protein- dithiol.
-!- Reduces insulin and some other proteins.

UniProtKB Entries (1)

O95881
TXD12_HUMAN
Homo sapiens
Thioredoxin domain-containing protein 12

PDB Structure

PDB 1SEN
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Endoplasmic reticulum protein Rp19
Liu, Z.-J., Chen, L., Tempel, W., Shah, A., Lee, D., Rose, J.P., Richardson, D.C., Richardson, J.S., Wang, B.-C.
To be Published
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