CATH Domain 1s2hA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.900	Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A
	3.30.900.10	HORMA domain

Domain Context

CATH Clusters

Superfamily	HORMA domain
Functional Family	Mitotic spindle assembly checkpoint protein MAD2A

Enzyme Information

UniProtKB Entries (1)

MD2L1_HUMAN

Homo sapiens

Mitotic spindle assembly checkpoint protein MAD2A

PDB Structure

PDB	1S2H
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	The Mad2 spindle checkpoint protein has two distinct natively folded states. Luo, X., Tang, Z., Xia, G., Wassmann, K., Matsumoto, T., Rizo, J., Yu, H. Nat.Struct.Mol.Biol.