CATH Domain 1rp5B04

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.710	Beta-lactamase
	3.40.710.10	DD-peptidase/beta-lactamase superfamily

Domain Context

CATH Clusters

Superfamily	DD-peptidase/beta-lactamase superfamily
Functional Family	Penicillin-binding protein 2x

Enzyme Information

UniProtKB Entries (1)

PBPX_STRPN

Streptococcus pneumoniae TIGR4

Penicillin-binding protein 2x

PDB Structure

PDB	1RP5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics. Pernot, L., Chesnel, L., Le Gouellec, A., Croize, J., Vernet, T., Dideberg, O., Dessen, A. J.Biol.Chem.