CATH Domain 1rf8A00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.760	RNA Cap, Translation Initiation Factor Eif4e
	3.30.760.10	RNA Cap, Translation Initiation Factor Eif4e

Domain Context

CATH Clusters

Superfamily	RNA Cap, Translation Initiation Factor Eif4e
Functional Family	Eukaryotic translation initiation factor 4E

Enzyme Information

UniProtKB Entries (1)

IF4E_YEAST

Saccharomyces cerevisiae S288C

Eukaryotic translation initiation factor 4E

PDB Structure

PDB	1RF8
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E. Gross, J.D., Moerke, N.J., von der Haar, T., Lugovskoy, A.A., Sachs, A.B., McCarthy, J.E., Wagner, G. Cell(Cambridge,Mass.)