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1 keywords

CATH Domain 1q7sB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.1490 Bit1
Homologous Superfamily 3.40.1490.10 Bit1

Domain Context

CATH Clusters

Superfamily Bit1
Functional Family Peptidyl-tRNA hydrolase 2

Enzyme Information

3.1.1.29
Aminoacyl-tRNA hydrolase.
based on mapping to UniProt Q9Y3E5
N-substituted aminoacyl-tRNA + H(2)O = N-substituted amino acid + tRNA.

UniProtKB Entries (1)

Q9Y3E5
PTH2_HUMAN
Homo sapiens
Peptidyl-tRNA hydrolase 2, mitochondrial

PDB Structure

PDB 1Q7S
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity.
De Pereda, J.M., Waas, W.F., Jan, Y., Ruoslahti, E., Schimmel, P., Pascual, J.
J.Biol.Chem.
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