CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family | Aclacinomycin methylesterase RdmC |
Enzyme Information
| 3.1.1.95 |
Aclacinomycin methylesterase.
based on mapping to UniProt Q54528
Aclacinomycin T + H(2)O = 15-demethylaclacinomycin T + methanol.
-!- The enzyme is involved in the modification of the aklavinone skeleton in the biosynthesis of anthracyclines in Streptomyces species.
|
UniProtKB Entries (1)
| Q54528 |
RDMC_STREF
Streptomyces purpurascens
Aclacinomycin methylesterase RdmC
|
PDB Structure
| PDB | 1Q0Z |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Streptomyces |
| Primary Citation |
Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism.
J.Biol.Chem.
|
