CATH Domain 1py2C00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1250	Growth Hormone; Chain: A;
	1.20.1250.10

Domain Context

CATH Clusters

Superfamily	1.20.1250.10
Functional Family	Interleukin-2

Enzyme Information

UniProtKB Entries (1)

IL2_HUMAN

Homo sapiens

Interleukin-2

PDB Structure

PDB	1PY2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Potent small-molecule binding to a dynamic hot spot on IL-2. Thanos, C.D., Randal, M., Wells, J.A. J.Am.Chem.Soc.