CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Orotate phosphoribosyltransferase

Enzyme Information

2.4.2.10
Orotate phosphoribosyltransferase.
based on mapping to UniProt P08870
Orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23.

UniProtKB Entries (1)

P08870
PYRE_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Orotate phosphoribosyltransferase

PDB Structure

PDB 1OPR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of the orotate phosphoribosyltransferase complexed with orotate and alpha-D-5-phosphoribosyl-1-pyrophosphate.
Scapin, G., Ozturk, D.H., Grubmeyer, C., Sacchettini, J.C.
Biochemistry
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