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1 keywords

CATH Domain 1oj5A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.450 Beta-Lactamase
Homologous Superfamily 3.30.450.20 PAS domain

Domain Context

CATH Clusters

Superfamily PAS domain
Functional Family Nuclear receptor coactivator

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt P70365
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (2)

P42226
STAT6_HUMAN
Homo sapiens
Signal transducer and activator of transcription 6
P70365
NCOA1_MOUSE
Mus musculus
Nuclear receptor coactivator 1

PDB Structure

PDB 1OJ5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Ncoa-1/Src-1 Pas-B Domain Bound to the Lxxll Motif of the Stat6 Transactivation Domain
Razeto, A., Ramakrishnan, V., Litterst, C.M., Giller, K., Griesinger, C., Carlomagno, T., Lakomek, N., Heimburg, T., Lodrini, M., Pfitzner, E., Becker, S.
J.Mol.Biol.
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