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CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside diphosphate kinase-like domain
Functional Family Nucleoside diphosphate kinase B

Enzyme Information

2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt P22392
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.
2.7.13.3
Histidine kinase.
based on mapping to UniProt P22392
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.

UniProtKB Entries (1)

P22392
NDKB_HUMAN
Homo sapiens
Nucleoside diphosphate kinase B

PDB Structure

PDB 1NSK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of a human nucleoside diphosphate kinase, NM23-H2.
Webb, P.A., Perisic, O., Mendola, C.E., Backer, J.M., Williams, R.L.
J.Mol.Biol.
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