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1 keywords

CATH Domain 1nhxA03

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.228 Phosphoenolpyruvate Carboxykinase; domain 3
Homologous Superfamily 3.90.228.20  

Domain Context

CATH Clusters

Superfamily 3.90.228.20
Functional Family phosphoenolpyruvate carboxykinase, cytosolic [GTP]

Enzyme Information

4.1.1.32
Phosphoenolpyruvate carboxykinase (GTP).
based on mapping to UniProt P35558
GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO(2).
-!- ITP can act as phosphate donor.

UniProtKB Entries (1)

P35558
PCKGC_HUMAN
Homo sapiens
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

PDB Structure

PDB 1NHX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
X-RAY STRUCTURES OF TWO XANTHINE INHIBITORS BOUND TO PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines
FOLEY, L.H., WANG, P., DUNTEN, P., RAMSEY, G., GUBLER, M.-L., WERTHEIMER, S.J.
Bioorg.Med.Chem.Lett.
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