CATH Domain 1mx6B00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.20	Ankyrin repeat-containing domain

Domain Context

CATH Clusters

Superfamily	Ankyrin repeat-containing domain
Functional Family	cyclin-dependent kinase 4 inhibitor C

Enzyme Information

UniProtKB Entries (1)

CDN2C_HUMAN

Homo sapiens

Cyclin-dependent kinase 4 inhibitor C

PDB Structure

PDB	1MX6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity Venkataramani, R.N., MacLachlan, T.K., Chai, X., El-Deiry, W.S., Marmorstein, R. J.Biol.Chem.