CATH Domain 1mwzA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.100

Domain Context

CATH Clusters

Superfamily	3.30.70.100
Functional Family	Zinc/cadmium/lead-transporting P-type ATPase

Enzyme Information

7.2.2.12	P-type Zn(2+) transporter. based on mapping to UniProt P37617 ATP + H(2)O + Zn(2+)(Side 1) = ADP + phosphate + Zn(2+)(Side 2). -!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- The enzyme, present in prokaryotes and photosynthetic eukaryotes, exports Zn(2+) and the related cations Cd(2+) and Pb(2+). -!- Formerly EC 3.6.3.5.
3.6.3.3	Cadmium-exporting ATPase. based on mapping to UniProt P37617 ATP + H(2)O + Cd(2+)(In) = ADP + phosphate + Cd(2+)(Out). -!- P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
7.2.2.-	Linked to the hydrolysis of a nucleoside triphosphate. based on mapping to UniProt P37617

UniProtKB Entries (1)

ZNTA_ECOLI

Escherichia coli K-12

Zinc/cadmium/lead-transporting P-type ATPase

PDB Structure

PDB	1MWZ
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	A new zinc-protein coordination site in intracellular metal trafficking: solution structure of the apo and Zn(II) forms of ZntA (46-118) Banci, L., Bertini, I., Ciofi-Baffoni, S., Finney, L.A., Outten, C.E., O'Halloran, T.V. J.Mol.Biol.