CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | GDP-mannose 6-dehydrogenase |
Enzyme Information
| 1.1.1.132 |
GDP-mannose 6-dehydrogenase.
based on mapping to UniProt P11759
GDP-D-mannose + 2 NAD(+) + H(2)O = GDP-D-mannuronate + 2 NADH.
-!- Also uses the corresponding deoxynucleoside diphosphate derivative as a substrate.
|
UniProtKB Entries (1)
| P11759 |
ALGD_PSEAE
Pseudomonas aeruginosa PAO1
GDP-mannose 6-dehydrogenase
|
PDB Structure
| PDB | 1MV8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure of GDP-mannose
dehydrogenase: A key enzyme in alginate
biosynthesis of P. aeruginosa
Biochemistry
|
