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1 keywords

CATH Domain 1m2nB02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.1600 SIR2/SIRT2 'Small Domain'
Homologous Superfamily 3.30.1600.10 SIR2/SIRT2 'Small Domain'

Domain Context

CATH Clusters

Superfamily SIR2/SIRT2 'Small Domain'
Functional Family

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt O28597

UniProtKB Entries (1)

O28597
NPD1_ARCFU
Archaeoglobus fulgidus DSM 4304
NAD-dependent protein deacylase 1

PDB Structure

PDB 1M2N
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for the NAD-dependent deacetylase mechanism of Sir2
Chang, J.H., Kim, H.C., Hwang, K.Y., Lee, J.W., Jackson, S.P., Bell, S.D., Cho, Y.
J.BIOL.CHEM.
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