CATH Classification
| Level | CATH Code | Description | 
|---|---|---|
|   | 3 | Alpha Beta | 
|   | 3.40 | 3-Layer(aba) Sandwich | 
|   | 3.40.50 | Rossmann fold | 
|   | 3.40.50.150 | Vaccinia Virus protein VP39 | 
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 | 
| Functional Family | Caffeic acid O-methyltransferase | 
Enzyme Information
| 2.1.1.68 | Caffeate O-methyltransferase. based on mapping to UniProt P28002 S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L- homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate. -!- 3,4-dihydroxybenzaldehyde and catechol can act as acceptor, more slowly. | 
UniProtKB Entries (1)
| P28002 | COMT1_MEDSA Medicago sativa Caffeic acid 3-O-methyltransferase | 
PDB Structure
| PDB | 1KYZ | 
| External Links | |
| Method | X-RAY DIFFRACTION | 
| Organism | Escherichia | 
| Primary Citation | Structural basis for the modulation of lignin monomer methylation by caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase. Plant Cell | 
