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CATH Classification

Domain Context

CATH Clusters

Superfamily Golgi alpha-mannosidase II
Functional Family Alpha-galactosidase

Enzyme Information

3.2.1.49
Alpha-N-acetylgalactosaminidase.
based on mapping to UniProt Q90744
Cleavage of non-reducing alpha-(1->3)-N-acetylgalactosamine residues from human blood group A and AB mucin glycoproteins, Forssman hapten and blood group A lacto series glycolipids.
-!- The human lysosomal enzyme is involved in the degradation of blood type A epitope.

UniProtKB Entries (1)

Q90744
NAGAB_CHICK
Gallus gallus
Alpha-N-acetylgalactosaminidase

PDB Structure

PDB 1KTC
External Links
Method X-RAY DIFFRACTION
Organism Pichia
Primary Citation
The 1.9 A structure of alpha-N-acetylgalactosaminidase: molecular basis of glycosidase deficiency diseases.
Garman, S.C., Hannick, L., Zhu, A., Garboczi, D.N.
Structure
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