CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.120 | Anthranilate synthase |
|
3.60.120.10 | Anthranilate synthase |
Domain Context
CATH Clusters
| Superfamily | Anthranilate synthase |
| Functional Family | Aminodeoxychorismate synthase, component I |
Enzyme Information
| 2.6.1.85 |
Aminodeoxychorismate synthase.
based on mapping to UniProt P05041
Chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate.
-!- Composed of two subunits, PabA and PabB. -!- In the absence of PabA and glutamine, PabB converts ammonia and chorismate into 4-amino-4-deoxychorismate. -!- PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB. -!- Coupled with EC 4.1.3.38, to form 4-aminobenzoate. -!- Formerly EC 6.3.5.8.
|
UniProtKB Entries (1)
| P05041 |
PABB_ECOLI
Escherichia coli K-12
Aminodeoxychorismate synthase component 1
|
PDB Structure
| PDB | 1K0G |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of Escherichia coli aminodeoxychorismate synthase: architectural conservation and diversity in chorismate-utilizing enzymes.
Biochemistry
|
