CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.2000 | Glycogen Phosphorylase B; |
Domain Context
CATH Clusters
| Superfamily | Glycogen Phosphorylase B; |
| Functional Family | Sterol 3-beta-glucosyltransferase UGT80A2 |
Enzyme Information
| 2.4.1.310 |
Vancomycin aglycone glucosyltransferase.
based on mapping to UniProt P96559
UDP-alpha-D-glucose + vancomycin aglycone = UDP + devancoaminyl- vancomycin.
-!- The enzyme from the bacterium Amycolatopsis orientalis is involved in the biosynthesis of the glycopeptide antibiotic chloroeremomycin.
|
UniProtKB Entries (1)
| P96559 |
GTFB_AMYOR
Amycolatopsis orientalis
Vancomycin aglycone glucosyltransferase
|
PDB Structure
| PDB | 1IIR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of the UDP-glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics.
Structure
|
