CATH Domain 1i3mA02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	UDP-glucose 4-epimerase

Enzyme Information

5.1.3.7	UDP-N-acetylglucosamine 4-epimerase. based on mapping to UniProt Q14376 UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine.
5.1.3.2	UDP-glucose 4-epimerase. based on mapping to UniProt Q14376 UDP-alpha-D-glucose = UDP-alpha-D-galactose. -!- Also acts on UDP-2-deoxyglucose.

UniProtKB Entries (1)

GALE_HUMAN

Homo sapiens

UDP-glucose 4-epimerase

PDB Structure

PDB	1I3M
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Pichia
Primary Citation	Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase. Thoden, J.B., Wohlers, T.M., Fridovich-Keil, J.L., Holden, H.M. J.Biol.Chem.