×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 1g88B00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.200 Tumour Suppressor Smad4
Homologous Superfamily 2.60.200.10  

Domain Context

CATH Clusters

Superfamily 2.60.200.10
Functional Family Mothers against decapentaplegic homolog

Enzyme Information

UniProtKB Entries (1)

Q13485
SMAD4_HUMAN
Homo sapiens
Mothers against decapentaplegic homolog 4

PDB Structure

PDB 1G88
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization.
Chacko, B.M., Qin, B., Correia, J.J., Lam, S.S., de Caestecker, M.P., Lin, K.
Nat.Struct.Biol.
CATH-Gene3D is a Global Biodata Core Resource Learn more...