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1 keywords

CATH Domain 1ehwB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.70 Alpha-Beta Plaits
Homologous Superfamily 3.30.70.141 Nucleoside diphosphate kinase-like domain

Domain Context

CATH Clusters

Superfamily Nucleoside diphosphate kinase-like domain
Functional Family Nucleoside diphosphate kinase

Enzyme Information

2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt O00746
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.

UniProtKB Entries (1)

O00746
NDKM_HUMAN
Homo sapiens
Nucleoside diphosphate kinase, mitochondrial

PDB Structure

PDB 1EHW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase.
Milon, L., Meyer, P., Chiadmi, M., Munier, A., Johansson, M., Karlsson, A., Lascu, I., Capeau, J., Janin, J., Lacombe, M.L.
J.Biol.Chem.
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